Signs You're a MTHFR

When it comes to determining if you have one or more copies of an MTHFR variant (namely C677T or A1298C), there is no sure-fire way to know for certain, aside from getting genetic testing. Even amongst those with a confirmed diagnosis, symptoms can be highly varied, depending on other genetic factors, environmental considerations, lifestyle, etc. However, there are certainly some indications that can point you and your naturopathic physician in the right direction. How can you determine that genetic testing for the MTHFR gene may be in order? The following signs may point to an MTHFR variant.

Common manifestations of an MTHFR variant:

-Food intolerances


-Brain fog

-Chemical sensitivity

-Anxiety and depression


-Recurrent infection

-Low immunity

-Chronic fatigue

-Thyroid imbalance

-Blood clots

-Chronic inflammation

-Eventual development of auto-immune disease


-Recurrent miscarriage

-Pregnancies with neural tube defects

-In infants, "tongue ties," "stork bite," and "sugar bug" markers may or may not be reliable indicators

This is, by no means, an exhaustive list. You may also notice that many of these symptoms are vague and can be indicators of many conditions. That's why so many people breathe a sigh a relief when they find out that all of their seemingly unrelated ailments were actually all stemming from a singular root cause! If you have struggled with several of the symptoms listed above and have never been able to get to the bottom of it, genetic testing for the MTHFR mutation may be a good choice for you.

How did you come to suspect that you may be a MTHFR? Tell us about it!

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